PROTAC CDK9 degrader-2 (compound 11c) is a potent and selective CDK9 degrader based on PROTAC, with an IC50 of 17 µM in MCF-7 cell lines. Natural product Wogonin (CDK ligand) binds ubiquitin E3 ligase Cereblon (CRBN) via a linker to form PROTAC[1].
Molecular Weight:
748.74
Purity:
99.22
CAS Number:
[2435721-30-3]
Formula:
C39H36N6O10
Target:
CDK,PROTACs
Application Notes:
MCE Product type: Reference compound
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