DC41SMe, a DC1 derivative, shows cytotoxicity in Ramos, Namalwa, and HL60/s cells with IC50s ranging from 18-25 pM. DC1, a simplified analogue of CC-1065, is an antibody conjugate of cytotoxic DNA alkylators for the targeted treatment of cancer[1][2].
Molecular Weight:
726.31
CAS Number:
[1354787-71-5]
Formula:
C38H36ClN5O4S2
Target:
ADC Payload
Application Notes:
MCE Product type: ADC Related
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