AN11736 is a CPSF3 inhibitor. AN11736 exerts a potent anti-trypsin effect by specifically inhibiting the activity of the trypanosome CPSF3 endonuclease, disrupting the mRNA maturation process. AN11736 exhibits IC50s against T. congolense and T. vivax of 0.14 and 1.3 nM, respectively. AN11736 exhibits strong anti-trypsin activity in mouse and cattle models[1][2].
Molecular Weight:
399.22
CAS Number:
[2152662-85-4]
Formula:
C21H23BFNO5
Target:
mRNA,Parasite
Application Notes:
MCE Product type: Reference compound
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