Estrone sulfate sodium is an inactive endogenous estrogen that can be converted into Estrone (HY-B0234) and Estradiol (HY-B0141). Estrone sulfate sodium is also a substrate of the OATP1B3 transporter. Estrone sulfate sodium can be converted into Estrone and Estradiol in normal mammary parenchymal cells. Estrone sulfate sodium stimulates the growth of nitrosomethylurea-induced mammary tumors in ovariectomized rats and the colony formation of dispersed nitrosomethylurea mammary cells, with conversion into Estrone and Estradiol occurring both in vivo and in vitro during this process. Estrone sulfate sodium is applicable to breast cancer-related research[1][2][3][4].
Molecular Weight:
372.41
Purity:
99.84
CAS Number:
[438-67-5]
Formula:
C18H21NaO5S
Target:
Endogenous Metabolite,Estrogen Receptor/ERR
Application Notes:
MCE Product type: Natural Products
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