12S-HHT (12(S)-HHTrE) is an enzymatic product of prostaglandin H2 (PGH2) derived from cyclooxygenase (COX)-mediated arachidonic acid metabolism. 12S-HHT is an endogenous ligand for BLT2 that fully activates BLT2 in vivo. 12S-HHT suppresses UV-induced IL-6 synthesis in keratinocytes, exerting an anti-inflammatory activity[1][2].
Molecular Weight:
280.40
Purity:
99
CAS Number:
[54397-84-1]
Formula:
C17H28O3
Target:
Endogenous Metabolite,Leukotriene Receptor
Application Notes:
MCE Product type: Reference compound1
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