3-Methylglutaric acid is a non-selective inhibitor of mitochondrial function and Na+, K+-ATPase, with an inhibition rate of 30% on rat cortical synaptosomal Na+, K+-ATPase. 3-Methylglutaric acid can induce reactive oxygen species (ROS) generation, thereby causing oxidative damage and inhibiting mitochondrial redox potential and ion pump function of cell membranes. 3-Methylglutaric acid can be used to study the neuropathological mechanisms of metabolic diseases and the role of oxidative stress-mediated neuronal damage in neurodegeneration[1][2][3][4].
Molecular Weight:
146.14
Purity:
98
CAS Number:
[626-51-7]
Formula:
C6H10O4
Target:
Mitochondrial Metabolism,Na+/K+ ATPase,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Natural Products
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