Lipoxin A4 (LXA4), an endogenous lipoxygenase-derived eicosanoid mediator, has potent dual pro-resolving and anti-inflammatory properties[1]. Lipoxin A4 inhibits proliferation and inflammatory cytokine/chemokine production of human epidermal keratinocytes (NHEKs) associated with the ERK1/2 and NF-kB pathways[2]. Lipoxin A4 inhibits serum amyloid A (SAA)-mediated IL-8 release with an IC50 value of 25.74 nM[3].
Molecular Weight:
352.47
Purity:
98.00
CAS Number:
[89663-86-5]
Formula:
C20H32O5
Target:
Endogenous Metabolite,Interleukin Related
Application Notes:
MCE Product type: Natural Products
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