Shield-2 is an efficient stabilizing ligand binding to the FKBP (F36V) protein with a dissociation constant of 29 nM. Shield-2 binds tightly to the FKBP mutants destabilizing domains and prevents degradation, thus providing small molecule regulation over intracellular protein levels[1][2].
Molecular Weight:
625.80
CAS Number:
[1013621-70-9]
Formula:
C35H51N3O7
Target:
FKBP
Application Notes:
MCE Product type: Reference compound
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