AKB-6899, a prolyl hydroxylase domain 3 (PHD3) inhibitor, is a selective HIF-2alpha stabilizer. AKB-6899 also increases soluble form of the VEGF receptor (sVEGFR-1) production from GM-CSF-treated macrophages, and has antitumor and antiangiogenic effects[1].
Molecular Weight:
290.25
Purity:
99.95
CAS Number:
[1007377-55-0]
Formula:
C14H11FN2O4
Target:
HIF/HIF Prolyl-Hydroxylase
Application Notes:
MCE Product type: Reference compound
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