AMG 7905 is a hypothermia-inducing transient receptor potential vanilloid type 1 (TRPV1) antagonist. AMG 7905 potentiates TRPV1 channels activation by protons and drives the reflectory inhibition of thermogenesis and tail-skin vasoconstriction, while potently blocking channel activation by capsaicin[1][2].
Molecular Weight:
483.55
Purity:
90.93
CAS Number:
[1026876-55-0]
Formula:
C25H24F3N5S
Target:
TRP Channel
Application Notes:
MCE Product type: Reference compound
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