CH5137291 is an orally active pure antagonist of the androgen receptor (AR), without generating agonist metabolites. CCH5137291 directly blocks the transfer of AR from the cytoplasm to the nucleus. H5137291 can completely inhibit tumor growth in cells and mouse models of castration-resistant prostate cancer models. CH5137291 can be used for the study of castration-resistant prostate cancer (CRPC)[1][2].
Molecular Weight:
469.46
CAS Number:
[1043446-39-4]
Formula:
C18H14F3N5O3S2
Target:
Androgen Receptor
Application Notes:
MCE Product type: Reference compound1
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