DS21412020, CAS [[1037366-37-2]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-113718
Supplier Catalog Number:
HY-113718
Alternative Catalog Number:
MCE-HY-113718-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
DS21412020 is a fluoroquinolone antibacterial agent. DS21412020 inhibits bacterial DNA gyrase (GyrA) and topoisomerase IV, leading to DNA breaks. DS21412020 exhibits significant activity against Gram-positive bacteria such as Staphylococcus aureus (MIC = 0.006 µg/mL), Streptococcus pneumoniae (MIC = 0.05 µg/mL), and Methicillin (HY-121544)-resistant Staphylococcus aureus (MIC = 0.2 µg/mL), and Gram-negative bacteria such as Escherichia coli (MIC = 0.006 µg/mL) and Pseudomonas aeruginosa (MIC = 0.78 µg/mL). DS21412020 significantly reduces bacterial load in mouse pneumonia and MRSA infection models. DS21412020 can be used in the development of next-generation quinolone antibiotics[1].
Molecular Weight:
435.42
CAS Number:
[1037366-37-2]
Formula:
C21H23F2N3O5
Target:
Bacterial,DNA/RNA Synthesis,Topoisomerase
Application Notes:
MCE Product type: Reference compound1
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