VUF5834 is a non-peptide chemokine receptor CXCR3 antagonist with non-competitive antagonistic and inverse agonistic activities. VUF5834 blocks the effects of CXCL10 and CXCL11 on human CXCR3, exhibits non-competitive antagonistic and inverse agonistic properties to CXCR3, and, except for TAK-779, has a slightly lower affinity for rodent CXCR3 than for primate CXCR3.
Molecular Weight:
515.69
CAS Number:
[860002-95-5]
Formula:
C31H41N5O2
Target:
CXCR
Application Notes:
MCE Product type: Reference compound
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