L524-0366 is a specific, dose-dependent TWEAK-Fn14 inhibitor. L524-0366 specifically binds to the Fn14 surface with a KD of 7.12 µM, competitively inhibiting the binding of Fn14 to TWEAK (inhibition rate reaching 16%). L524-0366 inhibits TWEAK-induced glioma cell migration without potential cytotoxic effects[1].
Molecular Weight:
308.79
Purity:
99.62
CAS Number:
[951612-19-4]
Formula:
C13H13ClN4OS
Target:
TNF Receptor
Application Notes:
MCE Product type: Reference compound
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