(R)-9b is a potent inhibitor of ACK1 tyrosine kinase (IC50=56 nM) with anticancer activity. (R)-9b exhibits selectivity for ACK1 but has inhibitory effects on JAK family kinases JAK2 and Tyk2. (R)-9b can be used in the study of hormone-regulated cancers such as prostate and breast cancer[1].
Molecular Weight:
402.92
Purity:
99.51
CAS Number:
[1655527-68-6]
Formula:
C20H27ClN6O
Target:
Ack1,JAK
Application Notes:
MCE Product type: Reference compound
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