SW-106 is a parathyroid hormone receptor 1 (PTHR1) antagonist. SW106 antagonizes PTHR1-mediated cAMP signaling induced by the peptide analog, M-PTH (1-11), as well as by the native PTH (1-9) sequence, as tethered to the extracellular end of transmembrane domain (TMD) helix-1 of the receptor. SW-106 can be used for the research of metabolic disease[1].
Molecular Weight:
361.31
CAS Number:
[1027921-53-4]
Formula:
C17H16F5NO2
Target:
PTHR
Application Notes:
MCE Product type: Reference compound
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