Z-Asp-CH2-DCB is an irreversible broad spectrum caspase inhibitor. Z-Asp-CH2-DCB also inhibits proteases with caspase-like activity. Z-D-CH2-DCB blocks the production of IL-1beta, TNF-alpha, IL-6, and IFN-gamma in staphylococcal enterotoxin B (SEB)-stimulated peripheral blood mononuclear cells (PBMC), and reduces SEB-1-stimulated T-cell proliferation in a dose-dependent manner. Z-Asp-CH2-DCB prevents SU5416-induced septal cell apoptosis and emphysema development[1][2][3].
Molecular Weight:
454.26
Purity:
99.64
CAS Number:
[153088-73-4]
Formula:
C20H17Cl2NO7
Target:
Apoptosis,Caspase
Application Notes:
MCE Product type: Reference compound
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