CUR61414 is a novel, potent and cell permeable Hedgehog signaling pathway inhibitor (IC50 =100-200 nM). CUR61414 is a small-molecule aminoproline class compound and selectively binds to smoothened (Smo) with a Ki value of 44 nM. CUR-61414 can induce apoptosis in cancer cells without affecting neighboring non-tumor cells[1][2].
Molecular Weight:
550.69
Purity:
99.04
CAS Number:
[334998-36-6]
Formula:
C31H42N4O5
Target:
Apoptosis,Hedgehog,Smo
Application Notes:
MCE Product type: Reference compound
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