PF-00356231 hydrochloride is a specific, non-peptidic, non-zinc chelating ligand and inhibitor of matrix metalloproteinase MMP-12 (IC50=1.4 µM). PF-00356231 hydrochloride binds to MMP-12 and forms PF-00356231/MMP-12 complex. PF-00356231 hydrochloride shows potency against MMP-13, MMP-8, MMP-9, MMP-3 with IC50s of 0.00065, 1.7, 0.98, 0.39 µM, respectively[1].
Molecular Weight:
464.96
Purity:
99.52
CAS Number:
[820223-77-6]
Formula:
C25H21ClN2O3S
Target:
MMP
Application Notes:
MCE Product type: Reference compound
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