PLX5622 hemifumarate is a highly selective brain penetrant and orally active CSF1R inhibitor (IC50=0.016 µM, Ki=5.9 nM). PLX5622 hemifumarate allows for extended and specific microglial elimination, preceding and during pathology development. PLX5622 hemifumarate demonstrates desirable PK properties in varies animals[1][2].
Molecular Weight:
453.45
Purity:
99.93
Formula:
C23H21F2N5O3
Target:
c-Fms
Application Notes:
MCE Product type: Reference compound
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