ONC1-13B is a potent androgen receptor (AR) antagonist with the activity of effectively inhibiting PSA expression in prostate cancer cells. ONC1-13B can effectively inhibit PSA expression and prostate cancer cell proliferation under DHT stimulation. ONC1-13B exerts its anti-tumor effect by preventing androgen from binding to AR and its nuclear translocation[1].
Molecular Weight:
492.45
CAS Number:
[1351185-54-0]
Formula:
C22H16F4N4O3S
Target:
Androgen Receptor
Application Notes:
MCE Product type: Reference compound
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