EC1169 is a cytotoxic maytansinoid conjugate that specifically binds to prostate-specific membrane antigen (PSMA). EC1169 precisely delivers the maytansinoid B hydrazide payload to PSMA-positive cells to exert antitumor activity. EC1169 only inhibits the growth of PSMA-positive cells but has no effect on PSMA-negative cells, and enables complete recovery in mice bearing PSMA-positive tumors. EC1169 exhibits safety with no body weight loss or major organ damage induced. EC1169 is used in studies of prostate cancer and other PSMA-expressing malignancies[1][2][3].
Molecular Weight:
1790.00
Purity:
98.06
CAS Number:
[1610413-96-1]
Formula:
C78H112N14O28S3
Target:
PSMA
Application Notes:
MCE Product type: Natural Products
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