NXT629 is a potent, selective, and competitive PPAR-alpha antagonist, with an IC50 of 77 nM for human PPARalpha, shows high selectivity over other nuclear hormone receptor, such as PPARdelta, PPARgamma, ERbeta, GR and TRbeta, IC50s are 6.0, 15, 15.2, 32.5 and >100 µM, respectively[1]. NXT629 has potent anti-tumor activity and inhibits experimental metastasis of cancer cell in animal models[2].
Molecular Weight:
609.78
Purity:
99.07
CAS Number:
[1454925-59-7]
Formula:
C35H39N5O3S
Target:
PPAR
Application Notes:
MCE Product type: Reference compound
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