Sotorasib-d7 (AMG-510-d7) is a deuterium-labeled Sotorasib (HY-114277). Sotorasib (AMG-510) is a first-in-class, orally bioavailable, and selective KRAS G12C covalent inhibitor. Sotorasib irreversibly inhibits KRAS G12C by locking it in an inactive GDP-bound state. Sotorasib leads to the regression of KRAS G12C-mutated locally advanced or metastatic non-small cell lung cancer (NSCLC)[1][2][3].
Molecular Weight:
567.64
Purity:
98.90
Formula:
C30H23D7F2N6O3
Target:
Isotope-Labeled Compounds,Ras
Application Notes:
MCE Product type: Isotope-Labeled Compounds
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