Sotorasib-d3 (AMG-510-d3) is deuterium labeled Sotorasib. Sotorasib (AMG-510) is a first-in-class, orally bioavailable, and selective KRAS G12C covalent inhibitor. Sotorasib irreversibly inhibits KRAS G12C by locking it in an inactive GDP-bound state. Sotorasib leads to the regression of KRAS G12C?mutated locally advanced or metastatic non?small cell lung cancer (NSCLC)[1][2][3][4][5][6].
Molecular Weight:
563.61
Formula:
C30H27D3F2N6O3
Target:
Isotope-Labeled Compounds,Ras
Application Notes:
MCE Product type: Isotope-Labeled Compounds
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