CCB02 is a selective CPAP-tubulin interaction inhibitor, binding to tubulin and competing for the CPAP binding site of beta-tubulin, with an IC50 of 689 nM, and shows potent anti-tumor activity. CCB02 shows no inhibition on the cell cycle- and centrosome-related kinases, or the phosphorylation status of Aurora A, Plk1, Plk2, CDK2, and CHK1[1].
Molecular Weight:
235.24
Purity:
99.93
CAS Number:
[2100864-57-9]
Formula:
C14H9N3O
Target:
Microtubule/Tubulin
Application Notes:
Reference compound
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