VZ185 is a potent, fast, and selective von Hippel-Lindau based dual degrader probe of BRD9 and BRD7 with DC50s of 4.5 and 1.8 nM, respectively. VZ185 is cytotoxic in EOL-1 and A-402 cells, with EC50s of 3 nM and 40 nM, respectively[1].
Molecular Weight:
995.21
Purity:
99.95
CAS Number:
[2306193-61-1]
Formula:
C53H67FN8O8S
Target:
Epigenetic Reader Domain,PROTACs
Application Notes:
Reference compound
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