cis-VZ185 is a VHL-based PROTACs degrader with the activity of degrading BRD9 and BRD7. cis-VZ185 can be optimized from suboptimal compounds by optimizing the connection mode and linker, and has efficient, rapid and selective degradation of BRD9 and its homologous protein BRD7.
Molecular Weight:
995.21
CAS Number:
[2306193-98-4]
Formula:
C53H67FN8O8S
Target:
Epigenetic Reader Domain,PROTACs
Application Notes:
Reference compound
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