DLK-IN-1 (Compound 14) is an orally active, blood-brain barrier-penetrable and selective inhibitor of dual leucine zipper kinase (DLK, MAP3K12) with a Ki value of 3 nM. DLK-IN-1 inhibits Flt3, PAK4, STK33 and TrkA. DLK-IN-1 reduces p-c-Jun. DLK-IN-1 can be used in Alzheimers disease research[1].
Molecular Weight:
423.43
Purity:
99.18
CAS Number:
[1620574-24-4]
Formula:
C20H24F3N5O2
Target:
FLT3,MAP3K,PAK,STK33,Trk Receptor
Application Notes:
MCE Product type: Reference compound
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