NVS-ZP7-4 is an inhibitor of the zinc transporter SLC39A7 (ZIP7) and indicates ER zinc levels. ZIP7 is an active molecular node in the Notch pathway and mediates ferroptosis. NVS-ZP7-4 induces ER stress and exerts a certain ferroptosis-inhibiting effect, reduces Erastin (HY-15763)-induced cell death[1][2].
Molecular Weight:
501.62
Purity:
98.85
CAS Number:
[2349367-89-9]
Formula:
C28H28FN5OS
Target:
Ferroptosis,SLC39 (Zinc Transporter)
Application Notes:
MCE Product type: Reference compound
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