BAY-293, a valuable chemical probe, blocks RAS activation via disruption of the KRAS-SOS1 interaction with an IC50 of 21 nM. BAY-293 is a potent inhibitor of Son of Sevenless 1 (SOS1). SOS1 is the guanine nucleotide exchange factor (GEF) and activator of RAS[1].
Molecular Weight:
448.58
Purity:
98.97
CAS Number:
[2244904-70-7]
Formula:
C25H28N4O2S
Target:
Ras,SOS1
Application Notes:
MCE Product type: Reference compound
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