SJFalpha is a selective p38alpha PROTAC degrader with a DC50 of 7.16 nM and Dmax of 97.4%. SJFalpha is far less effective at degrading p38delta (DC50 = 299 nM). SJFalphacan be used for the research of cancer, such as breast cancer[1]. (Structure Note: Pink: p38alpha ligand (HY-45124), Blue: VHL ligand (HY-125845))
Molecular Weight:
1120.27
Purity:
99.61
CAS Number:
[2254609-27-1]
Formula:
C59H67F2N7O11S
Target:
p38 MAPK,PROTACs
Application Notes:
MCE Product type: Reference compound
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