YZ129 is an inhibitor of the HSP90-calcineurin-NFAT pathway against glioblastoma, directly binding to heat shock protein 90 (HSP90) with an IC50 of 820 nM on NFAT nuclear translocation. YZ129-induced GBM cell-cycle arrest at the G2/M phase promotes apoptosis and inhibited tumor cell proliferation and migration[1].
Molecular Weight:
300.31
Purity:
99.85
CAS Number:
[1643120-60-8]
Formula:
C19H12N2O2
Target:
Apoptosis,HSP
Application Notes:
MCE Product type: Reference compound
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