Zetomipzomib (KZR-616) maleate, a first-in-class immunoproteasome inhibitor, selectively targets the LMP7 (IC50: 39/57 nM=hLMP7/mLMP7) and LMP2 (IC50: 131/179 nM=hLMP2/mLMP2) subunits of the immunoproteasome. Zetomipzomib maleate has the potential for the research of multiple autoimmune diseases[1][2].
Molecular Weight:
702.75
Purity:
99.84
CAS Number:
[2170983-62-5]
Formula:
C34H46N4O12
Target:
Proteasome
Application Notes:
MCE Product type: Reference compound
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