INH14 is a cell permeable inhibitor of IKKalpha/IKKbeta, with IC50s of 8.97 and 3.59 µM, respectively. INH14 inhibits the IKKalpha/beta-dependent TLR inflammatory response. INH14 also inhibits downstream of TAK1/TAB1 and NF-kB pathways. Anti-inflammatory and anti-cancer activity[1].
Molecular Weight:
240.30
Purity:
98
CAS Number:
[200134-22-1]
Formula:
C15H16N2O
Target:
IKK
Application Notes:
MCE Product type: Reference compound
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