AES-135, a hydroxamic acid-based pan-HDAC inhibitor, prolongs survival in an orthotopic mouse model of pancreatic cancer. AES-135 inhibits HDAC3, HDAC6, HDAC8, and HDAC11 with IC50s ranging from 190-1100 nM[1].
Molecular Weight:
693.66
Purity:
98.21
CAS Number:
[2361659-61-0]
Formula:
C33H29F6N3O5S
Target:
HDAC
Application Notes:
MCE Product type: Reference compound
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