Rineterkib (compound B) is an orally available ERK1 and ERK2 inhibitor in the treatment of a proliferative disease characterized by activating mutations in the MAPK pathway. The activity is particularly related to the treatment of KRAS-mutant NSCLC, BRAF-mutant NSCLC, KRAS-mutant pancreatic cancer, KRAS-mutant colorectal cancer (CRC) and KRAS-mutant ovarian cancer. Rineterkib hydrochloride can also inhibit RAF[1][2].
Molecular Weight:
578.42
Purity:
99.70
CAS Number:
[1715025-32-3]
Formula:
C26H27BrF3N5O2
Target:
ERK,Raf
Application Notes:
MCE Product type: Dye Reagents
* VAT and and shipping costs not included. Errors and price changes excepted