RVX-297 is a potent, orally active BET bromodomain inhibitor with selectivity for BD2. RVX-297 shows IC50s of 0.08, 0.05, and 0.02 µM for BRD2(BD2), BRD3(BD2), and BRD4(BD2), respectively. RVX-297 suppresses inflammatory gene expression in multiple immune cell types. RVX-297 is effective in acute inflammation and autoimmunity models[1][2].
Molecular Weight:
423.50
Purity:
95.00
CAS Number:
[1044871-04-6]
Formula:
C24H29N3O4
Target:
Epigenetic Reader Domain
Application Notes:
MCE Product type: Reference compound
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