PRMT/HKMT-IN-1, CAS [[1020399-52-3]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-114510
Supplier Catalog Number:
HY-114510
Alternative Catalog Number:
MCE-HY-114510-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
PRMT/HKMT-IN-1 is an epigenetic multi-target protein arginine methyltransferases (PRMTs) and histone lysine methyltransferases (HKMTs) inhibitor. PRMT/HKMT-IN-1 inhibits Aspergillus nidulans RmtA with an IC50 of 29 µM. PRMT/HKMT-IN-1 inhibits human PRMT1, p300/CBP HAT, CARM1, SET7, SIRT1 and SIRT2. PRMT/HKMT-IN-1 inhibits methylation of histone H3K4, H4R3, and H3R17 residues. CBP/p300-IN-23 induces apoptosis, arrests cell cycle in S phase, and triggers granulocytic differentiation in leukemia cells. PRMT/HKMT-IN-1 can be used for the research of leukemia[1].
