TT01001 is a selective and orally active mitoNEET agonist and a monoamine oxidase B (MAO-B) inhibitor (IC50 = 8.84 µM). TT01001 does not activate PPARgamma but interacts with MitoNEET. TT01001 attenuates oxidative stress and neuronal apoptosis by preventing mitoNEET-mediated mitochondrial dysfunction. TT01001 improves type II diabetes and ameliorates mitochondrial function of mice. TT01001 can used for the studies of type II diabetes and neurological disorders [1][2][3].
Molecular Weight:
376.30
Purity:
99.38
CAS Number:
[1022367-69-6]
Formula:
C15H19Cl2N3O2S
Target:
Apoptosis,Mitochondrial Metabolism,Monoamine Oxidase,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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