N-3-oxo-dodecanoyl-L-Homoserine lactone (3-oxo-C12-HSL) is a bacterial quorum-sensing signaling molecule produced by P. aeruginosa and strains of the B. cepacia complex[1][2].Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density.N-3-oxo-dodecanoyl-L-Homoserine lactone induces the production of IL-8 in 16HBE human bronchial epithelial cells[3].
Molecular Weight:
297.39
Purity:
99.88
CAS Number:
[168982-69-2]
Formula:
C16H27NO4
Target:
Apoptosis,Bacterial,Caspase,ERK,NF-kappaB,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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