Ebselen oxide, the selenone analogue of Ebselen, covalently modifies diguanylate cyclase (DGC) to inhibit c-di-GMP-receptor interactions and reduces DGC activity. Ebselen oxide also inhibits alginate production (IC50=14 µM) by Pseudomonas aeruginosa. Ebselen oxide inhibits HDAC1, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, and HDAC9 (IC50 ranging from 0.2 to 4.7 µM)[1][2][3].
Molecular Weight:
290.18
Purity:
98
CAS Number:
[104473-83-8]
Formula:
C13H9NO2Se
Target:
Guanylate Cyclase
Application Notes:
MCE Product type: Reference compound
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