Satigrel (E5510) is a potent inhibitor of platelet aggregation. Satigrel inhibits collagen- and arachidonic acid-induced platelet aggregation through preventing thromboxane A2 synthesis by selective inhibition of the target enzyme, PGHS1, which exists in platelets. Satigrel inhibits PGHS1 (IC50: 0.081 µM) and PGHS2 (IC50: 5.9 µM). Satigrel is against Type III PDE, Type V and Type II (IC50: 15.7 µM, 39.8 µM and 62.4 µM, respectively)[1].
Molecular Weight:
337.37
Purity:
99.85
CAS Number:
[111753-73-2]
Formula:
C20H19NO4
Target:
Prostaglandin Receptor
Application Notes:
MCE Product type: Reference compound
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