Palifosfamide (tromethamine) is a synthetic alkylating agent with potential antineoplastic activity. As the stabilized active metabolite of ifosfamide, palifosfamide (tromethamine) irreversibly alkylates and crosslinks DNA through GC base pairs. This leads to an inhibition of DNA replication and ultimately cell death. Compared to ifosfamide, palifosfamide (tromethamine) is less toxic.
Molecular Weight:
342.16
CAS Number:
[1070409-31-2]
Formula:
C8H22Cl2N3O5P
Target:
DNA Alkylator/Crosslinker
Application Notes:
MCE Product type: Reference compound
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