EM-800, an orally active anti-estrogen, serves as an antagonist to the transcriptional functions of estrogen receptors alpha (ERalpha) and beta (ERbeta). EM-800 possesses anticancer activity, capable of inhibiting the growth of breast cancer induced by 7,12-Dimethylbenz[a]anthracene (DMBA) (HY-W011845). Furthermore, in ovariectomized animals, EM-800 effectively slows down bone loss. Additionally, EM-800 shows potential in the research of breast and endometrial cancers, while exerting beneficial effects on bone and lipid metabolism[1][2].
Molecular Weight:
625.79
CAS Number:
[182167-03-9]
Formula:
C39H47NO6
Target:
Estrogen Receptor/ERR
Application Notes:
MCE Product type: Reference compound
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