Pyridoxal isonicotinoyl hydrazone is an orally active and lipophilic iron-specific chelator that acts as a non-competitive inhibitor of ferrochelatase (FECH) by binding iron ions. Pyridoxal isonicotinoyl hydrazone disrupts heme biosynthesis, leading to reduced FECH stability and increased protoporphyrin IX (PPIX) accumulation. Pyridoxal isonicotinoyl hydrazone is promising for research of iron-overload diseases (e.g., beta-thalassemia)[1][2][3][4][5][6].
Molecular Weight:
286.29
Purity:
99.96
CAS Number:
[737-86-0]
Formula:
C14H14N4O3
Target:
Biochemical Assay Reagents,Ferrochelatase
Application Notes:
MCE Product type: Reference compound
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