Pumafentrine is an orally active, potent dual PDE3/PDE4 inhibitor. Pumafentrine dose-dependently ameliorates the clinical score and colonic TNFalpha production in murine Dextran sulphate sodium (DSS, HY-116282C)-induced colitis in a preventive setting[1].
Molecular Weight:
477.64
CAS Number:
[207993-12-2]
Formula:
C29H39N3O3
Target:
Phosphodiesterase (PDE)
Application Notes:
MCE Product type: Reference compound
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