(E,E)-GLL398, CAS [[2077980-83-5]] Preis auf Anfrage

Product Overview

• Article Name: (E,E)-GLL398, CAS [[2077980-83-5]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-114770
• Supplier Catalog Number: HY-114770
• Alternative Catalog Number: MCE-HY-114770-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

(E,E)-GLL398 is a selective estrogen receptor degrader with potent binding activity to ERalpha (IC50 = 1.14 nM). (E,E)-GLL398 can effectively degrade ERalpha in MCF-7 breast cancer cells (IC50 = 0.21 µM). The introduced boronic acid group of (E,E)-GLL398 gives it superior oral bioavailability, with an AUC of 36.9 µgh/mL in rats, which is significantly higher than that of GW7604[1].

Product Properties

• Molecular Weight: 398.26
• CAS Number: [2077980-83-5]
• Formula: C25H23BO4
• Target: Estrogen Receptor/ERR

Application Notes

• Application Notes: MCE Product type: Reference compound