Bunolol ((Rac)-Bunolol) is a beta-adrenergic receptor blocker. Bunolol antagonizes the beta-receptor agonist activity induced by Isoproterenol (HY-B0468) and Dichloroisoproterenol. Bunolol reduces the heart rate and mean blood pressure of anesthetized dogs. Bunolol decreases spontaneous motor activity and Amphetamine-induced hyperactivity in rats, potentiates Pentobarbital-induced hypnosis in mice, and protects rats from extensor tonic convulsions induced by maximal electroshock[1][2][3].
Molecular Weight:
291.39
CAS Number:
[27591-01-1]
Formula:
C17H25NO3
Target:
Adrenergic Receptor
Application Notes:
MCE Product type: Reference compound
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