TDRL-551 is a potent replication protein A (RPA) inhibitor (IC50 = 18 µM). TDRL-551 inhibits RPA-DNA interaction and increases the anti-cancer efficacy of Platinum (Pt)-based chemotherapy. TDRL-551 can be used for the research of cancer, such as non-small cell lung cancer (NSCLC)[1].
Molecular Weight:
591.83
Purity:
99.84
CAS Number:
[1644626-43-6]
Formula:
C25H23ClIN3O4
Target:
DNA/RNA Synthesis
Application Notes:
MCE Product type: Reference compound
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